Recently, the 32nd European Society of Hypertension (ESH) Annual Meeting was held in Milan, Italy, which highlights current international research status and trends in the pathogenesis, major clinical research results, prevention and treatment strategies and the latest understanding of hypertension, etc. Meantime, European Guidelines on Hypertension 2023 was released during the annual meeting in which the diagnostic criteria, treatment threshold, treatment goal and drug treatment of hypertension are updated and expanded based upon the latest evidence, which will provide guidance on scientific management for hypertension patients.
Doctoral student Wang Yang from the team of Professor Mu Jianjun of the First Affiliated Hospital (FAH) of Xi 'an Jiaotong University (XJTU) presented their latest research results at this annual meeting. The team delivered oral presentations to illustrate the association between blood pressure variability and renal function and the association between cardiovascular risk factors and vascular aging, which have been widely recognized and highly approved by the scholars attending the annual meeting. The findings of these two original studies have been published in Hypertension, a top-notch journal in the field of hypertension.
Based on Hanzhong Adolescent Hypertension Cohort Study, Wang Yang gave a presentation entitled "Associations of long-term visit-to-visit blood pressure variability and subclinical renal damage and albuminuria in adulthood: a 30-year prospective cohort study". In this article, the associations between long-term visit-to-visit blood pressure variability and subclinical renal damage and albuminuria during adulthood were comprehensively analyzed for the first time. From childhood to adulthood, the larger the blood pressure variability, the higher the risk of subclinical renal damage and albuminuria, suggesting that early identification of long-term blood pressure variability contributes to predicting the long-term risk of renal and cardiovascular diseases, and is of significance to deeply understand the association between hypertension and chronic kidney disease and explore prompt prevention and control strategies.
Subsequently, Wang Yang delivered a presentation entitled "Early-life cardiovascular risk factor trajectories and vascular aging in midlife: a 30-year prospective cohort study". The study found that maintaining cardiovascular risk factors from childhood, including high systolic blood pressure (SBP), body mass index (BMI ) and heart rate (HR) trajectories, is intimately correlated with the increased risk of vascular aging in midlife. In addition, respondents who have been long-term exposed to more cardiovascular risk factors have a higher risk of vascular aging. These findings prompt that continuous monitoring of cardiovascular risk factors from childhood may be one of the important approaches to identify individuals with high-risk cardiovascular disease in early life, which is of significance for in-depth understanding of the association between traditional cardiovascular risk factors and vascular aging, exploring early prevention and control, and lowering long-term cardiovascular risk.
