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Name:Chen Wei

Department:Department of Clinical Laboratory

Professional title:Chief Docimaster

Focus area:Clinical molecular diagnosis, screening and identification of tumor markers


Professional memberships

Committee Member     Laboratory Medicine, Chinese Medical Association

Committee Member    Association of Medical Genetics, Chinese Medical Association

Standing Committee Member      Laboratory Physician Branch,  Chinese Medical Doctor Association

Vice Chairman Committee Member    Association of Laboratory Medicine, Shaanxi Medical Association

Vice Chairman Committee Member     Association of Medical Genetics, Shaanxi Medical Association

 

Academic and scientific achievements

1UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion[J].FEBS Lett. 2008 ,82(13):1919-1927.

2Long non-coding RNA UCA1 regulated cell cycle distribution via CREB through PI3-K dependent pathway in bladder carcinoma cells[J]. Gene,2012,496(1):8-16.

3Ets-2 regulates cell apoptosis via the Akt pathway, through the regulation of urothelial cancer associated 1, a long non-coding RNA, in bladder cancer cells[J].PLoS One,2013 Sep 12;8(9):e73920.

4Long non-coding RNA UCA1 promotes glycolysis by upregulating hexokinase 2 through the mTOR-STAT3/microRNA143 pathway[J]. Cancer Sci, 2014, 105 (8): 951-955.

5Long non-coding RNA UCA1 promotes cisplatin/gemcitabine resistance through CREB modulating miR-196a-5p in bladder cancer cells[J].Cancer Letters. 2016,382(1):64-76.

6Long non‐coding RNA urothelial cancer‐associated 1 promotes bladder cancer cell migration and invasion by way of the hsa-miR-145-ZEB1/2-FSCN1 pathway[J].Cancer Sci,2016 ,107(1): 18–27.

7Gene expression profiling of microRNAs associated with UCA1 in bladder cancer cells[J].Int J Oncol,2016,48(4):1617-1627.

8LncRNA UCA1 Promotes Mitochondrial Function of Bladder Cancer via the MiR-195/ARL2 Signaling Pathway[J].Cellular physiology and Biochemistry,2017,43(6):2548-2561.

9The characteristics of screening and confirmatory test results for HIV in Xi'an, China[J]. PLoS One,2017,12(7):e0180071.

10apid diagnosis of extrapulmonary tuberculosis with Xpert Mycobacterium tuberculosis/rifampicin assay[J]. Journal of medical midrobiology,2017,66:910-914.

11miR-33a-5p enhances the sensitivity of lung adenocarcinoma cells to celastrol by regulating mTOR signaling[J]. Int J Oncol,2018, 52(4):1328-1338.

 

Awards and honors

The study of "Expression of heat shock protein 70 and glycoprotein 96 in digestive tract tumors and their immunoadjuvant function" won the Second Prize for Scientific and Technological Achievements in Shaanxi Province in 2015.

 

 

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