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Multidisciplinary Collaboration Enables Resection of a Rare Malignant Tumor in a 3-Day-Old Newborn

Updated: Mar 23, 2026
From: Department of Pediatric Surgery
Edited by: Liu Huiting
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Recently, a multidisciplinary team at the Land Port Division of the First Affiliated Hospital (FAH) of Xi’an Jiaotong University (XJTU) worked together to successfully resect a rare, giant malignant intra-abdominal tumor in a male infant who was only 3 days old. The infant is currently in stable condition, with smooth recovery progress. The infant was urgently referred from Hanzhong due to a massive abdominal mass. Postoperative pathology confirmed a grade Ⅲ gastric-origin immature teratoma. Fewer than 100 such cases have been reported worldwide, and its occurrence in newborns is particularly rare.

The primary key to successful treatment was precise preoperative contrast-enhanced CT examination. In view of the newborn’s small vessels and fragile circulation, the Department of Radiology, together with the Department of Pediatric Surgery and the Department of Anesthesiology, tailored a low-radiation, rapid scanning protocol. They accurately calculated the contrast agent dose and injection flow rate and completed the scan with the support of the anesthesia team. The imaging clearly delineated the tumor’s relationship with adjacent vessels and organs, providing a precise “battle map” for surgery.

During the surgery, the team of the Department of Anesthesiology and Perioperative Medicine precisely calculated the dosage of anesthetic agents in micrograms, using advanced equipment to monitor and adjust the infant’s breathing, circulation, and temperature in real-time, ensuring a safe and stable operating conditions for the procedure. Professor Liu Shiqi’s pediatric surgery team, guided by preoperative imaging, confirmed that the tumor originated from the gastric wall. The team successfully completed the tumor resection in 2 hours and 40 minutes, while carefully preserving adjacent vital organs and tissues.

Postoperatively, the infant was transferred to the neonatal intensive care unit (NICU), where, under professional care and monitoring, the infant was successfully weaned off the ventilator, restored gastrointestinal function, and began oral feeding. The infant is now ready to be transferred to a general ward. The success of this treatment was made possible by the FAH’s multidisciplinary collaboration platform, which broke down disciplinary barriers and established a seamless life-saving relay from preoperative assessment and intraoperative procedures to postoperative monitoring, fully demonstrating the technological capabilities and clinical excellence of modern precision medicine in pediatrics.

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