Recently, prestigious international journals of Clinical Nutrition and BMC Medicine reported the new progress made by Professor Shi Bingyin's team in the field of metabolic syndrome.

In 2020, the team led by Professor Shi Bingyin from Department of Endocrinology took dietary intervention as a breakthrough, and pioneered in carrying out the first international clinical trial of low-carbonhydrate diet, 8-h time-restricted eating and two combined interventions in metabolic syndrome (ClinicalTrials.gov, NCT04475822). The experimental results proved that both low-carbonhydrate diet and time-restricted eating can significantly mitigate obesity and glucose indexes in patients with metabolic syndrome. The efficacy of two combined interventions can be further improved. After published in Cell Reports Medicine, a top international academic journal, these findings have aroused widespread attention worldwide, and this article has became one of the Most Read articles in this journal, and received the award of "Cell Press China Paper of the Year 2022".

Subsequently, the team further studied the effects of low-carbonhydrate diet and 8-h time-restricted eating on heart and thyroid function. The results showed that time-restricted eating and low-carbonhydrate diet can significantly alleviate myocardial metabolism and thyroid function of patients with metabolic syndrome. Time-restricted eating can also significantly improve the quality of life of patients. This result further confirms the beneficial effect of scientific dietary intervention on patients with metabolic syndrome, which is of guiding significance for clinical intervention and treatment for patients with metabolic syndrome.

Recently, the team's serial research of "Dietary intervention model for metabolic syndrome" -Interventional study of time-restricted eating in the morning and evening for overweight populations with metabolic syndrome (ClinicalTrials.gov, NCT06018415) has come to an end. This study is expected to provide a more scientific basis for selecting the time window of time-restricted eating.