From October 22 to 25, 2023, the American College of Surgeons (ACS) Annual Meeting, an international high-level meeting, was held in Boston, Massachusetts, USA. At the invitation of the Organizing Committee, 9 team members of Surgical Dreamworks, including Associate Research Fellow Xiang Junxi, Associate Research Fellow Yan Xiaopeng, doctoral students Peng Ziyang and Wang Zhibo, attended the meeting for oral presentations or posters, and they also exchanged and shared research results with more than 12,000 professionals from over 100 countries around the world.
At the meeting, Peng Ziyang introduced intelligent surgical assistant device. By effectively real-time registering preoperative three-dimensional reconstruction with surgical images during laparoscopic hepatectomy, deep anatomical structures were identified, and the whole operation process was optimized and early warning was achieved, providing safer and more accurate surgical advice for surgeons, thereby significantly reducing the incidence of surgical complications and shortening the operation time. Wang Zhibo illustrated magnet-assisted vascular anastomosis in rats, and evaluated vascular wall thickness and hemodynamics of rats by precise vascular modeling in rats before operation. Finally, it was found that customized magnet-assisted vascular anastomosis equipment based on intelligent analysis yielded better hemodynamic recovery, more reasonable magnetic field intensity and more matching magnetic ring size than standard magnetic anastomosis ring, which is expected to be applied in clinical practice in the future.
Associate Research Fellow Xiang Junxi delivered a presentation entitled “Low Prognostic Nutritional index is Common and Associated with Poor Outcomes Following Curativeintent Resection for Gastro-entero-pancreatic Neuroendocrine Tumors”.
Zhang Nan contributed a poster demonstrating the gender difference that women are less tolerant of alcohol than men and are more likely to develop alcoholic liver disease, and reproduced this difference through animal models. Meantime, the mechanism of SRY gene in the process of gender difference and its association with liver alcohol-metabolizing enzymes were unraveled. Wu Xiaoning delivered a presentation reporting that male, as an independent risk factor of liver fibrosis, aggravated the progress of male liver fibrosis, leading to the gender difference of liver fibrosis diseases between male and female populations. This gender difference was reproduced in animal models, and the specific mechanism of SRY gene during the process of such gender difference was studied.
Zhang Wei contributed a poster introducing that after radical resection of liver cancer, men are more prone to recurrence of liver cancer than women, and this gender difference was confirmed in mouse models. Subsequent mechanism research suggested that SRY gene may promote the recurrence of liver cancer by remodeling tumor microenvironment.
Six members delivered oral presentations. Yan Xiaopeng from magnetic surgery team gave an oral presentation entitled “Magnetic Compression Anastomosis for Reconstruction of Digestive Tract After Total Gastrectomy in Beagle Model”. Zhang Miaomiao delivered a presentation entitled “Application of Y-Z Deformable Magnetic Ring for Recanalization of Transanal Single-Access Rectal Stricture”. Xu Shuqin gave a presentation entitled “Experimental study on esophagojejunal magnamosis in rats”, etc. Seven members contributed e-Poster, such as “Development of Yan-Lyu Classification of Post-liver Transplantation Biliary Stricture for Magnetic Recanalization, Tracheoesophageal Fistula Treated With Magnetic Compression Technique: An Experimental Study”, etc.
