Professor He Jianjun is the Director of the Department of Breast Surgery. He is a Doctorial supervisor.

Vice Chairman   Society of Breast Surgery of Chinese Research Hospital Association

Standing Committee Member   Chinese Society of Breast Surgeons and Committee of Breast Disease Training Expert and Chinese College of Surgeons, Chinese Medical Doctor Association

Member   Breast Disease Group, Maternal and Child Health Branch of Chinese Preventive Medicine Association

Deputy Secretary-General   Breast Cancer Collaborative Group in West China

Chairman   Surgical Oncology Committee of Shaanxi Anti-Cancer Association

Chairman   Breast Disease Committee of Shaanxi Province Health Care Association

Vice Chairman   Breast Cancer Committee of Shaanxi Anti-Cancer Association

Executive Director   Shaanxi Anti-Cancer Association

Professor He Jianjun has hosted multiple National Natural Science Foundation of China and scientific research projects at the provincial and ministerial levels, and participated in the Precision Medicine Research of the National Key Research and Development Project of Ministry of Science and Technology of China. He has published over 80 papers related to breast cancer including 26 SCI papers and 8 papers with an impact factor > 5 as follows:

(1) Zhang H, Lu H, Xiang L, Bullen JW, Zhang C, Samanta D, Gilkes DM, He J, Semenza GL*. HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells.Proc Natl AcadSci U S A, 2015, 112(45):E6215-6223.

(2) Zhang H, Ren Y, Tang X, Wang K, Liu Y, Zhang L, Li X, Liu P, Zhao C, He J*. Vascular Normalization Induced by Sinomenine Hydrochloride Results in Suppressed Mammary Tumor Growth and Metastasis. Sci Rep, 2015, 5: 8888.

(3) Wang R, Li X, Zhang H, Wang K, He J*. Cell-free circulating tumor DNA analysis for breast cancer and its clinical utilization as a biomarker. Oncotarget, 2017, 8 (43):75742-75755.

(4) Li X, Wang K, Ren Y, Zhang L, Tang X, Zhang H, Zhao C, Liu P, Zhang J, He J*. MAPK signaling mediates sinomenine hydrochloride-induced human breast cancer cell death via both reactive oxygen species-dependent and -independent pathways: an in vitro and in vivo study.Cell Death Dis, 2014, 5:e1356.

(5) Jiang Zhu, Zhengzhi Zou, PeipeiNie, Xiaoni Kou, Baoyan Wu, Songmao Wang, Zhangjun Song,Jianjun He*. Downregulation of microRNA-27b-3p enhances tamoxifen resistance in breast cancer by increasing NR5A2 and CREB1 expression.Cell Death Dis. 2016 Nov 3;7(11):e2454.

(6) Jian Zhang, Xiao Li, Rong Huang, Wei-Liang Feng,Ya-Nan Kong, Feng Xu,Lin Zhao, Qing-Kun Song, Jing Li, Bao-Ning Zhang, Jin-Hu Fan, You-Lin Qiao,Xiao-Ming Xie, Shan Zheng, Jian-Jun He* and Ke Wang*. A nomogram to predict the probability of axillary lymph node metastasis in female patients with breast cancer in China: A nationwide, multicenter, 10-year epidemiological study. Oncotarget. 2017 May 23;8(21):35311-35325.

(7) Xiao Li, Pingping Li, Chao Liu, Yu Ren, XiaojiangTang, Ke Wang*, Jianjun He*. Sinomenine hydrochloride inhibits breast cancer metastasisby attenuating inflammation-related epithelial–mesenchymaltransition and cancer stemness. Oncotarge.2017 Feb 21;8(8):13560-13574.

(8) Nan H, Han L, Ma J, Yang C, Su R, He J*. STX3 represses the stability of the tumor suppressor PTEN to activate the PI3K-Akt-mTOR signaling and promotes the growth of breast cancer cells.BiochimBiophysActaMol Basis Dis. 2018 May;1864(5 Pt A):1684-1692.

Professor He Jianjun was awarded the 2^nd and 3^rd prize of Science and Technology Progress Award of Shaanxi Province.